This JAMA essay on the fundamental and irreversible change AI will make in our understanding of the body and disease, is important. It put its finger on the essence of the matter: how once that black box gets really going,  most of our ideas and knowledge about disease will be forgotten, indeed, outmoded and made as useless as the fluxes and winds, humors and seasons of premodern medicine.

See the essay here: https://jamanetwork.com/journals/jama/fullarticle/2814246